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Stay away from use when using any oral drug that is depending on threshold concentrations for efficacy. Interactions listed are consultant examples and do not include things like all attainable medical illustrations.
The choice to reclassify the drugs has become manufactured next a consultation with impartial professionals, healthcare pros and individuals. 992 responses were being obtained.
amiodarone will raise the stage or outcome of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Stops conversion of codeine to its Lively metabolite morphine.
clobazam decreases outcomes of codeine by impacting hepatic more info enzyme CYP2D6 metabolism. Use Warning/Watch. Prevents conversion of codeine to its Lively metabolite morphine.
Beginning on the 25mg dose more info may additionally be encouraged Should you have any chance aspects which make you much more vulnerable to Unwanted effects (like click here diabetes for example).
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